BDBM100969 US8524909, 51

SMILES: Cc1cc(cc(C)c1C(=O)N[C@H]1COCC[C@@H]1N1CCCC1)C(F)(F)F

InChI Key: InChIKey=MADMGRSONIGUEX-HOTGVXAUSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 100969   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Glycine transporter 1b (Bos taurus (Bovine))	BDBM100969 (US8524909, 51) Show SMILES Cc1cc(cc(C)c1C(=O)N[C@H]1COCC[C@@H]1N1CCCC1)C(F)(F)F |r| Show InChI InChI=1S/C19H25F3N2O2/c1-12-9-14(19(20,21)22)10-13(2)17(12)18(25)23-15-11-26-8-5-16(15)24-6-3-4-7-24/h9-10,15-16H,3-8,11H2,1-2H3,(H,23,25)/t15-,16-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	25.3	n/a	n/a	n/a	n/a	n/a	0
Hoffmann-La Roche Inc. US Patent					Assay Description Glycine uptake inhibition assay.				US Patent US8524909 (2013) BindingDB Entry DOI: 10.7270/Q2QJ7FXS
					More data for this Ligand-Target Pair