BDBM101233 US8524722, 81
SMILES: CN(C)C\C=C\C(=O)N1Cc2sc3ncnc(Nc4ccc(F)c(Cl)c4)c3c2C1
InChI Key: InChIKey=LCOUDBVKMKTAKW-ONEGZZNKSA-N
Data: 1 IC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Epidermal growth factor receptor (Homo sapiens (Human)) | BDBM101233 (US8524722, 81) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 12 | n/a | n/a | n/a | n/a | 7.0 | 22 |
Bayer Intellectual Property GmbH US Patent | Assay Description EGFR inhibitory activity of compounds of the present invention is quantified employing the EGFR HTRF assay. | US Patent US8524722 (2013) BindingDB Entry DOI: 10.7270/Q2B856RQ | |||||||||||
More data for this Ligand-Target Pair |