BDBM101674 US9695160, 19::US9796707, Compound 19

SMILES: FC(F)(F)c1ccc(N2CCN(Cc3ccccc3)CC2)c(NC(=O)c2ccco2)c1

InChI Key: InChIKey=WJSTURLRVIKCBZ-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 101674   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Serine/threonine-protein kinase SRPK1 (Homo sapiens (Human))	BDBM101674 (US9695160, 19 | US9796707, Compound 19) Show SMILES FC(F)(F)c1ccc(N2CCN(Cc3ccccc3)CC2)c(NC(=O)c2ccco2)c1 Show InChI InChI=1S/C23H22F3N3O2/c24-23(25,26)18-8-9-20(19(15-18)27-22(30)21-7-4-14-31-21)29-12-10-28(11-13-29)16-17-5-2-1-3-6-17/h1-9,14-15H,10-13,16H2,(H,27,30)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	US Patent	n/a	n/a	14.1	n/a	n/a	n/a	n/a	n/a	n/a
The University of Nottingham; NewSouth Innovations PTY Limited US Patent					Assay Description Candidate compounds were screened by the Kinase-Glo assay (Promega; Koresawa and Okabe, 2004), the results of which are shown in Table 1 and Table 2....				US Patent US9796707 (2017) BindingDB Entry DOI: 10.7270/Q2125VTM
					More data for this Ligand-Target Pair
SRSF protein kinase 1 (SRPK1) (Homo sapiens (Human))	BDBM101674 (US9695160, 19 | US9796707, Compound 19) Show SMILES FC(F)(F)c1ccc(N2CCN(Cc3ccccc3)CC2)c(NC(=O)c2ccco2)c1 Show InChI InChI=1S/C23H22F3N3O2/c24-23(25,26)18-8-9-20(19(15-18)27-22(30)21-7-4-14-31-21)29-12-10-28(11-13-29)16-17-5-2-1-3-6-17/h1-9,14-15H,10-13,16H2,(H,27,30)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	US Patent	n/a	n/a	14	n/a	n/a	n/a	n/a	n/a	30
The University of Nottingham; NewSouth Innovations PTY Limited US Patent					Assay Description Candidate compounds were screened by the Kinase-Glo assay (Promega; Koresawa and Okabe, 2004), the results of which are shown in Table 1 and Table 2....				US Patent US9695160 (2017) BindingDB Entry DOI: 10.7270/Q2639MW1
					More data for this Ligand-Target Pair