BDBM101737 US9695160, 32::US9796707, Compound 32

SMILES: COc1cccc(CN2CCN(CC2)c2ccc(cc2NC(=O)c2ccc(o2)-c2ccncc2)C(F)(F)F)c1

InChI Key: InChIKey=LETPCCBWSPAYDT-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 101737   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Serine/threonine-protein kinase SRPK1 (Homo sapiens (Human))	BDBM101737 (US9695160, 32 | US9796707, Compound 32) Show SMILES COc1cccc(CN2CCN(CC2)c2ccc(cc2NC(=O)c2ccc(o2)-c2ccncc2)C(F)(F)F)c1 Show InChI InChI=1S/C29H27F3N4O3/c1-38-23-4-2-3-20(17-23)19-35-13-15-36(16-14-35)25-6-5-22(29(30,31)32)18-24(25)34-28(37)27-8-7-26(39-27)21-9-11-33-12-10-21/h2-12,17-18H,13-16,19H2,1H3,(H,34,37)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	1.55E+3	n/a	n/a	n/a	n/a	n/a	n/a
The University of Nottingham; NewSouth Innovations PTY Limited US Patent					Assay Description Candidate compounds were screened by the Kinase-Glo assay (Promega; Koresawa and Okabe, 2004), the results of which are shown in Table 1 and Table 2....				US Patent US9796707 (2017) BindingDB Entry DOI: 10.7270/Q2125VTM
					More data for this Ligand-Target Pair
SRSF protein kinase 1 (SRPK1) (Homo sapiens (Human))	BDBM101737 (US9695160, 32 | US9796707, Compound 32) Show SMILES COc1cccc(CN2CCN(CC2)c2ccc(cc2NC(=O)c2ccc(o2)-c2ccncc2)C(F)(F)F)c1 Show InChI InChI=1S/C29H27F3N4O3/c1-38-23-4-2-3-20(17-23)19-35-13-15-36(16-14-35)25-6-5-22(29(30,31)32)18-24(25)34-28(37)27-8-7-26(39-27)21-9-11-33-12-10-21/h2-12,17-18H,13-16,19H2,1H3,(H,34,37)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	1.55E+3	n/a	n/a	n/a	n/a	n/a	30
The University of Nottingham; NewSouth Innovations PTY Limited US Patent					Assay Description Candidate compounds were screened by the Kinase-Glo assay (Promega; Koresawa and Okabe, 2004), the results of which are shown in Table 1 and Table 2....				US Patent US9695160 (2017) BindingDB Entry DOI: 10.7270/Q2639MW1
					More data for this Ligand-Target Pair