BDBM102519 US8536175, 69::US8815901, 69

SMILES: CN1CCN(Cc2cnc(NC(=O)c3ccc(-c4cscc4C)c4nccnc34)[nH]2)CC1

InChI Key: InChIKey=IOFZHVYMWJLIQZ-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 102519   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Fibroblast growth factor receptor 3 (Homo sapiens (Human))	BDBM102519 (US8536175, 69 | US8815901, 69) Show SMILES CN1CCN(Cc2cnc(NC(=O)c3ccc(-c4cscc4C)c4nccnc34)[nH]2)CC1 Show InChI InChI=1S/C23H25N7OS/c1-15-13-32-14-19(15)17-3-4-18(21-20(17)24-5-6-25-21)22(31)28-23-26-11-16(27-23)12-30-9-7-29(2)8-10-30/h3-6,11,13-14H,7-10,12H2,1-2H3,(H2,26,27,28,31)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	25
Novartis AG US Patent					Assay Description The assay has been run at room temperature on a liquid handling robot. To the assay plates containing 50 mL compound or control solutions, 4.5 uL of ...				US Patent US8815901 (2014) BindingDB Entry DOI: 10.7270/Q2XG9PT8
					More data for this Ligand-Target Pair
Fibroblast growth factor receptor 3 (Homo sapiens (Human))	BDBM102519 (US8536175, 69 | US8815901, 69) Show SMILES CN1CCN(Cc2cnc(NC(=O)c3ccc(-c4cscc4C)c4nccnc34)[nH]2)CC1 Show InChI InChI=1S/C23H25N7OS/c1-15-13-32-14-19(15)17-3-4-18(21-20(17)24-5-6-25-21)22(31)28-23-26-11-16(27-23)12-30-9-7-29(2)8-10-30/h3-6,11,13-14H,7-10,12H2,1-2H3,(H2,26,27,28,31)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Novartis AG US Patent					Assay Description Protein kinase activity measured by the microfluidic caliper method.				US Patent US8536175 (2013) BindingDB Entry DOI: 10.7270/Q27D2SSH
					More data for this Ligand-Target Pair