BDBM102556 US8536172, I-5
SMILES: CN([C@H]1CC[C@@H](CC1)Nc1nccc(n1)-n1ccc2c(cccc12)N1CCN(CC1)C(C)=O)S(C)(=O)=O
InChI Key: InChIKey=WXVQYEDPGNFMIL-MEMLXQNLSA-N
Data: 2 IC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Mitogen-activated protein kinase 8 (Homo sapiens (Human)) | BDBM102556![]() (US8536172, I-5) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 105 | n/a | n/a | n/a | n/a | 7.5 | n/a |
Roche Palo Alto LLC US Patent | Assay Description JNK activity was measured by phosphorylation of GST-ATF2 (19-96) with [gamma-33P] ATP. | US Patent US8536172 (2013) BindingDB Entry DOI: 10.7270/Q23N222K | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Mitogen-activated protein kinase 8 (Homo sapiens (Human)) | BDBM102556![]() (US8536172, I-5) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 10.3 | n/a | n/a | n/a | n/a | 7.5 | n/a |
Roche Palo Alto LLC US Patent | Assay Description JNK activity was measured by phosphorylation of GST-ATF2 (19-96) with [gamma-33P] ATP. | US Patent US8536172 (2013) BindingDB Entry DOI: 10.7270/Q23N222K | |||||||||||
More data for this Ligand-Target Pair |