BDBM104376 US8575186, 139

SMILES: Cn1c2CC3CCC(N3)c2c2cc(cc(F)c12)S(=O)(=O)c1csc2ccccc12

InChI Key: InChIKey=JLVIWUPZBQHIEA-UHFFFAOYSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 104376   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
5-hydroxytryptamine receptor 6 (Homo sapiens (Human))	BDBM104376 (US8575186, 139) Show SMILES Cn1c2CC3CCC(N3)c2c2cc(cc(F)c12)S(=O)(=O)c1csc2ccccc12 |THB:10:9:8:6.5,1:2:8:6.5| Show InChI InChI=1S/C22H19FN2O2S2/c1-25-18-8-12-6-7-17(24-12)21(18)15-9-13(10-16(23)22(15)25)29(26,27)20-11-28-19-5-3-2-4-14(19)20/h2-5,9-12,17,24H,6-8H2,1H3	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	0.470	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Albany Molecular Research, Inc. US Patent					Assay Description The relative affinities of the various compounds for the 5-HT6 receptor were measured in a radioligand binding assay, using a sintillation proximity ...				US Patent US8575186 (2013) BindingDB Entry DOI: 10.7270/Q2BR8QTS
					More data for this Ligand-Target Pair