BDBM104460 US8575186, 223/224::US8575186, 240

SMILES: COc1cc(cc2c3C4CCC(Cc3n(C)c12)N4)S(=O)(=O)c1cn(C)c2ccccc12

InChI Key: InChIKey=DADFLUITEZWZLO-UHFFFAOYSA-N

Data: 2 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 104460   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
5-hydroxytryptamine receptor 6 (Homo sapiens (Human))	BDBM104460 (US8575186, 223/224 | US8575186, 240) Show SMILES COc1cc(cc2c3C4CCC(Cc3n(C)c12)N4)S(=O)(=O)c1cn(C)c2ccccc12 |THB:6:7:17:9.10,14:13:17:9.10| Show InChI InChI=1S/C24H25N3O3S/c1-26-13-22(16-6-4-5-7-19(16)26)31(28,29)15-11-17-23-18-9-8-14(25-18)10-20(23)27(2)24(17)21(12-15)30-3/h4-7,11-14,18,25H,8-10H2,1-3H3	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	0.990	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Albany Molecular Research, Inc. US Patent					Assay Description The relative affinities of the various compounds for the 5-HT6 receptor were measured in a radioligand binding assay, using a sintillation proximity ...				US Patent US8575186 (2013) BindingDB Entry DOI: 10.7270/Q2BR8QTS
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 6 (Homo sapiens (Human))	BDBM104460 (US8575186, 223/224 | US8575186, 240) Show SMILES COc1cc(cc2c3C4CCC(Cc3n(C)c12)N4)S(=O)(=O)c1cn(C)c2ccccc12 |THB:6:7:17:9.10,14:13:17:9.10| Show InChI InChI=1S/C24H25N3O3S/c1-26-13-22(16-6-4-5-7-19(16)26)31(28,29)15-11-17-23-18-9-8-14(25-18)10-20(23)27(2)24(17)21(12-15)30-3/h4-7,11-14,18,25H,8-10H2,1-3H3	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	2.40	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Albany Molecular Research, Inc. US Patent					Assay Description The relative affinities of the various compounds for the 5-HT6 receptor were measured in a radioligand binding assay, using a sintillation proximity ...				US Patent US8575186 (2013) BindingDB Entry DOI: 10.7270/Q2BR8QTS
					More data for this Ligand-Target Pair