BDBM104464 US8575186, 227

SMILES: COc1cc(cc2c3C4CCC(Cc3n(C)c12)N4C)S(=O)(=O)c1ccccc1

InChI Key: InChIKey=HTZXRCIYXVRXGI-UHFFFAOYSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 104464   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
5-hydroxytryptamine receptor 6 (Homo sapiens (Human))	BDBM104464 (US8575186, 227) Show SMILES COc1cc(cc2c3C4CCC(Cc3n(C)c12)N4C)S(=O)(=O)c1ccccc1 |THB:6:7:17:9.10,14:13:17:9.10| Show InChI InChI=1S/C22H24N2O3S/c1-23-14-9-10-18(23)21-17-12-16(28(25,26)15-7-5-4-6-8-15)13-20(27-3)22(17)24(2)19(21)11-14/h4-8,12-14,18H,9-11H2,1-3H3	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	0.680	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Albany Molecular Research, Inc. US Patent					Assay Description The relative affinities of the various compounds for the 5-HT6 receptor were measured in a radioligand binding assay, using a sintillation proximity ...				US Patent US8575186 (2013) BindingDB Entry DOI: 10.7270/Q2BR8QTS
					More data for this Ligand-Target Pair