Found 6 hits for monomerid = 104914 Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
Suppressor of tumorigenicity 14 protein
(Homo sapiens (Human)) | BDBM104914
![PNG](/data/jpeg/tenK10/BindingDB_104914.png) (CHEMBL507322 | US8569313, Inhibitor 26)Show SMILES NCCC(=O)Nc1cccc(c1)S(=O)(=O)N[C@@H](Cc1cccc(c1)C(N)=N)C(=O)N1CCN(CC1)C(=O)OCc1ccccc1 |r| Show InChI InChI=1S/C31H37N7O6S/c32-13-12-28(39)35-25-10-5-11-26(20-25)45(42,43)36-27(19-23-8-4-9-24(18-23)29(33)34)30(40)37-14-16-38(17-15-37)31(41)44-21-22-6-2-1-3-7-22/h1-11,18,20,27,36H,12-17,19,21,32H2,(H3,33,34)(H,35,39)/t27-/m0/s1 | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![](/images/AffyNet_logo.png)
| CHEMBL PC cid PC sid UniChem
Similars
| US Patent
| 6.10 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
The Medicines Company (Leipzig) GmbH
US Patent
| Assay Description Inhibition assay using matriptase enzyme |
US Patent US8569313 (2013)
BindingDB Entry DOI: 10.7270/Q2639ND5 |
More data for this Ligand-Target Pair | |
Suppressor of tumorigenicity 14 protein
(Homo sapiens (Human)) | BDBM104914
![PNG](/data/jpeg/tenK10/BindingDB_104914.png) (CHEMBL507322 | US8569313, Inhibitor 26)Show SMILES NCCC(=O)Nc1cccc(c1)S(=O)(=O)N[C@@H](Cc1cccc(c1)C(N)=N)C(=O)N1CCN(CC1)C(=O)OCc1ccccc1 |r| Show InChI InChI=1S/C31H37N7O6S/c32-13-12-28(39)35-25-10-5-11-26(20-25)45(42,43)36-27(19-23-8-4-9-24(18-23)29(33)34)30(40)37-14-16-38(17-15-37)31(41)44-21-22-6-2-1-3-7-22/h1-11,18,20,27,36H,12-17,19,21,32H2,(H3,33,34)(H,35,39)/t27-/m0/s1 | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![](/images/AffyNet_logo.png)
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 7.5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
The Medicines Company (Leipzig) GmbH
Curated by ChEMBL
| Assay Description Inhibition of matriptase (unknown origin) |
Bioorg Med Chem Lett 19: 1960-5 (2009)
Article DOI: 10.1016/j.bmcl.2009.02.047 BindingDB Entry DOI: 10.7270/Q2J96681 |
More data for this Ligand-Target Pair | |
Plasminogen
(Homo sapiens (Human)) | BDBM104914
![PNG](/data/jpeg/tenK10/BindingDB_104914.png) (CHEMBL507322 | US8569313, Inhibitor 26)Show SMILES NCCC(=O)Nc1cccc(c1)S(=O)(=O)N[C@@H](Cc1cccc(c1)C(N)=N)C(=O)N1CCN(CC1)C(=O)OCc1ccccc1 |r| Show InChI InChI=1S/C31H37N7O6S/c32-13-12-28(39)35-25-10-5-11-26(20-25)45(42,43)36-27(19-23-8-4-9-24(18-23)29(33)34)30(40)37-14-16-38(17-15-37)31(41)44-21-22-6-2-1-3-7-22/h1-11,18,20,27,36H,12-17,19,21,32H2,(H3,33,34)(H,35,39)/t27-/m0/s1 | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![](/images/AffyNet_logo.png)
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 1.30E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
The Medicines Company (Leipzig) GmbH
Curated by ChEMBL
| Assay Description Inhibition of plasmin (unknown origin) |
Bioorg Med Chem Lett 19: 1960-5 (2009)
Article DOI: 10.1016/j.bmcl.2009.02.047 BindingDB Entry DOI: 10.7270/Q2J96681 |
More data for this Ligand-Target Pair | |
Prothrombin
(Homo sapiens (Human)) | BDBM104914
![PNG](/data/jpeg/tenK10/BindingDB_104914.png) (CHEMBL507322 | US8569313, Inhibitor 26)Show SMILES NCCC(=O)Nc1cccc(c1)S(=O)(=O)N[C@@H](Cc1cccc(c1)C(N)=N)C(=O)N1CCN(CC1)C(=O)OCc1ccccc1 |r| Show InChI InChI=1S/C31H37N7O6S/c32-13-12-28(39)35-25-10-5-11-26(20-25)45(42,43)36-27(19-23-8-4-9-24(18-23)29(33)34)30(40)37-14-16-38(17-15-37)31(41)44-21-22-6-2-1-3-7-22/h1-11,18,20,27,36H,12-17,19,21,32H2,(H3,33,34)(H,35,39)/t27-/m0/s1 | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet ![](/images/AffyNet_logo.png)
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 1.40E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
The Medicines Company (Leipzig) GmbH
Curated by ChEMBL
| Assay Description Inhibition of thrombin (unknown origin) |
Bioorg Med Chem Lett 19: 1960-5 (2009)
Article DOI: 10.1016/j.bmcl.2009.02.047 BindingDB Entry DOI: 10.7270/Q2J96681 |
More data for this Ligand-Target Pair | |
Urokinase-type plasminogen activator
(Homo sapiens (Human)) | BDBM104914
![PNG](/data/jpeg/tenK10/BindingDB_104914.png) (CHEMBL507322 | US8569313, Inhibitor 26)Show SMILES NCCC(=O)Nc1cccc(c1)S(=O)(=O)N[C@@H](Cc1cccc(c1)C(N)=N)C(=O)N1CCN(CC1)C(=O)OCc1ccccc1 |r| Show InChI InChI=1S/C31H37N7O6S/c32-13-12-28(39)35-25-10-5-11-26(20-25)45(42,43)36-27(19-23-8-4-9-24(18-23)29(33)34)30(40)37-14-16-38(17-15-37)31(41)44-21-22-6-2-1-3-7-22/h1-11,18,20,27,36H,12-17,19,21,32H2,(H3,33,34)(H,35,39)/t27-/m0/s1 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![](/images/AffyNet_logo.png)
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 3.30E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
The Medicines Company (Leipzig) GmbH
Curated by ChEMBL
| Assay Description Inhibition of uPA (unknown origin) |
Bioorg Med Chem Lett 19: 1960-5 (2009)
Article DOI: 10.1016/j.bmcl.2009.02.047 BindingDB Entry DOI: 10.7270/Q2J96681 |
More data for this Ligand-Target Pair | |
Coagulation factor X
(Homo sapiens (Human)) | BDBM104914
![PNG](/data/jpeg/tenK10/BindingDB_104914.png) (CHEMBL507322 | US8569313, Inhibitor 26)Show SMILES NCCC(=O)Nc1cccc(c1)S(=O)(=O)N[C@@H](Cc1cccc(c1)C(N)=N)C(=O)N1CCN(CC1)C(=O)OCc1ccccc1 |r| Show InChI InChI=1S/C31H37N7O6S/c32-13-12-28(39)35-25-10-5-11-26(20-25)45(42,43)36-27(19-23-8-4-9-24(18-23)29(33)34)30(40)37-14-16-38(17-15-37)31(41)44-21-22-6-2-1-3-7-22/h1-11,18,20,27,36H,12-17,19,21,32H2,(H3,33,34)(H,35,39)/t27-/m0/s1 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![](/images/AffyNet_logo.png)
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 1.90E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
The Medicines Company (Leipzig) GmbH
Curated by ChEMBL
| Assay Description Inhibition of factor 10a (unknown origin) |
Bioorg Med Chem Lett 19: 1960-5 (2009)
Article DOI: 10.1016/j.bmcl.2009.02.047 BindingDB Entry DOI: 10.7270/Q2J96681 |
More data for this Ligand-Target Pair | |