BDBM104920 US8569313, Inhibitor 35

SMILES: COc1ccc(cc1)-c1cccc(c1)S(=O)(=O)NC(Cc1cccc(CN)c1)C(=O)N1CCC(CCN)CC1

InChI Key: InChIKey=VAZFEYPFKDVWTR-UHFFFAOYSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 104920   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Matriptase (Homo sapiens (Human))	BDBM104920 (US8569313, Inhibitor 35) Show SMILES COc1ccc(cc1)-c1cccc(c1)S(=O)(=O)NC(Cc1cccc(CN)c1)C(=O)N1CCC(CCN)CC1 |w:18.20| Show InChI InChI=1S/C30H38N4O4S/c1-38-27-10-8-25(9-11-27)26-6-3-7-28(20-26)39(36,37)33-29(19-23-4-2-5-24(18-23)21-32)30(35)34-16-13-22(12-15-31)14-17-34/h2-11,18,20,22,29,33H,12-17,19,21,31-32H2,1H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	145	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
The Medicines Company (Leipzig) GmbH US Patent					Assay Description Inhibition assay using matriptase enzyme				US Patent US8569313 (2013) BindingDB Entry DOI: 10.7270/Q2639ND5
					More data for this Ligand-Target Pair