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SMILES: N#Cc1ccc(cc1OC1CNC1)-c1ccccc1

InChI Key: InChIKey=WHKUBBHWMNRGHD-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 105020   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
5-hydroxytryptamine receptor 7 (Rattus norvegicus (rat))	BDBM105020 (US8575364, 29) Show SMILES N#Cc1ccc(cc1OC1CNC1)-c1ccccc1 Show InChI InChI=1S/C16H14N2O/c17-9-14-7-6-13(12-4-2-1-3-5-12)8-16(14)19-15-10-18-11-15/h1-8,15,18H,10-11H2	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Janssen Pharmaceutica NV US Patent					Assay Description Receptor binding was performed using membrane fractions prepared from the HEK-293 cell line recombinantly expressing rat 5-HT7 receptors (NCBI access...				US Patent US8957059 (2015) BindingDB Entry DOI: 10.7270/Q22Z1472
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 7 (Rattus norvegicus (rat))	BDBM105020 (US8575364, 29) Show SMILES N#Cc1ccc(cc1OC1CNC1)-c1ccccc1 Show InChI InChI=1S/C16H14N2O/c17-9-14-7-6-13(12-4-2-1-3-5-12)8-16(14)19-15-10-18-11-15/h1-8,15,18H,10-11H2	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Janssen Pharmaceutica NV US Patent					Assay Description Compound affinity for the rat 5-HT7 receptor subtype was evaluated by competitive radioligand binding assay using 5-carboxamido[H3]typtamine ([3H]5-C...				US Patent US8575364 (2013) BindingDB Entry DOI: 10.7270/Q2J9651G
					More data for this Ligand-Target Pair