BDBM105033 US8575364, 42

SMILES: Cc1ccc(cc1C)-c1ccc(Cl)cc1OC1CNC1

InChI Key: InChIKey=WOLAWKPRSBWWRL-UHFFFAOYSA-N

Data: 2 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 105033   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
5-hydroxytryptamine receptor 7 (Rattus norvegicus (rat))	BDBM105033 (US8575364, 42) Show SMILES Cc1ccc(cc1C)-c1ccc(Cl)cc1OC1CNC1 Show InChI InChI=1S/C17H18ClNO/c1-11-3-4-13(7-12(11)2)16-6-5-14(18)8-17(16)20-15-9-19-10-15/h3-8,15,19H,9-10H2,1-2H3	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	210	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Janssen Pharmaceutica NV US Patent					Assay Description Receptor binding was performed using membrane fractions prepared from the HEK-293 cell line recombinantly expressing rat 5-HT7 receptors (NCBI access...				US Patent US8957059 (2015) BindingDB Entry DOI: 10.7270/Q22Z1472
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 7 (Rattus norvegicus (rat))	BDBM105033 (US8575364, 42) Show SMILES Cc1ccc(cc1C)-c1ccc(Cl)cc1OC1CNC1 Show InChI InChI=1S/C17H18ClNO/c1-11-3-4-13(7-12(11)2)16-6-5-14(18)8-17(16)20-15-9-19-10-15/h3-8,15,19H,9-10H2,1-2H3	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	210	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Janssen Pharmaceutica NV US Patent					Assay Description Compound affinity for the rat 5-HT7 receptor subtype was evaluated by competitive radioligand binding assay using 5-carboxamido[H3]typtamine ([3H]5-C...				US Patent US8575364 (2013) BindingDB Entry DOI: 10.7270/Q2J9651G
					More data for this Ligand-Target Pair