BDBM105216 US8580778, 2

SMILES: O=c1c(c[nH]n1-c1cc(ncn1)N1CCN(CC1)C1CCC1)-n1ccnn1

InChI Key: InChIKey=WIMZEUVQQDDDSS-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 105216   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Hypoxia-inducible factor prolyl hydroxylase 4 (HIF) (Homo sapiens (Human))	BDBM105216 (US8580778, 2) Show SMILES O=c1c(c[nH]n1-c1cc(ncn1)N1CCN(CC1)C1CCC1)-n1ccnn1 Show InChI InChI=1S/C17H21N9O/c27-17-14(25-5-4-20-22-25)11-21-26(17)16-10-15(18-12-19-16)24-8-6-23(7-9-24)13-2-1-3-13/h4-5,10-13,21H,1-3,6-9H2	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	880	n/a	n/a	n/a	n/a	n/a	n/a
Bayer Intellectual Property GmbH US Patent					Assay Description In vitro tests for determination of the activity and selectivity of HIF prolyl 4-hydroxylase inhibitors. Hydroxylated HIF bonds specifically to the ...				US Patent US8580778 (2013) BindingDB Entry DOI: 10.7270/Q21C1VH5
					More data for this Ligand-Target Pair