BDBM105559 US10047086, 95::US10640503, Example 95::US9695168, 95

SMILES: COC(=O)N(C)c1ccc(cc1)-c1c(nc(N2CCC(CC2)N(C)C)c2cncn12)-c1ccc(cc1)C#N

InChI Key: InChIKey=AOSIDEYTBFNZCD-UHFFFAOYSA-N

Data: 3 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 105559   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Lysine-specific histone demethylase 1A [151-852] (Homo sapiens (Human))	BDBM105559 (US10047086, 95 | US10640503, Example 95 | US969516...) Show SMILES COC(=O)N(C)c1ccc(cc1)-c1c(nc(N2CCC(CC2)N(C)C)c2cncn12)-c1ccc(cc1)C#N Show InChI InChI=1S/C29H31N7O2/c1-33(2)23-13-15-35(16-14-23)28-25-18-31-19-36(25)27(26(32-28)21-7-5-20(17-30)6-8-21)22-9-11-24(12-10-22)34(3)29(37)38-4/h5-12,18-19,23H,13-16H2,1-4H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	<50	n/a	n/a	n/a	n/a	7.5	25
Incyte Corporation US Patent					Assay Description LANCE LSD1/KDM1A demethylase assay¿10 uL of 1 nM LSD-1 enzyme (ENZO BML-SE544-0050) in the assay buffer (50 mM Tris, pH 7.5, 0.01% Tween-20, 25 mM Na...				US Patent US9695168 (2017) BindingDB Entry DOI: 10.7270/Q2SX6BCD
					More data for this Ligand-Target Pair
Lysine-specific histone demethylase 1A (Homo sapiens (Human))	BDBM105559 (US10047086, 95 | US10640503, Example 95 | US969516...) Show SMILES COC(=O)N(C)c1ccc(cc1)-c1c(nc(N2CCC(CC2)N(C)C)c2cncn12)-c1ccc(cc1)C#N Show InChI InChI=1S/C29H31N7O2/c1-33(2)23-13-15-35(16-14-23)28-25-18-31-19-36(25)27(26(32-28)21-7-5-20(17-30)6-8-21)22-9-11-24(12-10-22)34(3)29(37)38-4/h5-12,18-19,23H,13-16H2,1-4H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	<50	n/a	n/a	n/a	n/a	n/a	n/a
Incyte Corporation US Patent					Assay Description LANCE LSD1/KDM1A demethylase assay-10 μL of 1 nM LSD-1 enzyme (ENZO BML-SE544-0050) in the assay buffer (50 mM Tris, pH 7.5, 0.01% Tween-20, 25 ...				US Patent US10640503 (2020)
					More data for this Ligand-Target Pair
Lysine-specific histone demethylase 1A (Homo sapiens (Human))	BDBM105559 (US10047086, 95 | US10640503, Example 95 | US969516...) Show SMILES COC(=O)N(C)c1ccc(cc1)-c1c(nc(N2CCC(CC2)N(C)C)c2cncn12)-c1ccc(cc1)C#N Show InChI InChI=1S/C29H31N7O2/c1-33(2)23-13-15-35(16-14-23)28-25-18-31-19-36(25)27(26(32-28)21-7-5-20(17-30)6-8-21)22-9-11-24(12-10-22)34(3)29(37)38-4/h5-12,18-19,23H,13-16H2,1-4H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	<50	n/a	n/a	n/a	n/a	7.5	n/a
Incyte Corporation US Patent					Assay Description LANCE LSD1/KDM1A demethylase assay-10 μL of 1 nM LSD-1 enzyme (ENZO BML-SE544-0050) in the assay buffer (50 mM Tris, pH 7.5, 0.01% Tween-20, 25 ...				US Patent US10047086 (2018) BindingDB Entry DOI: 10.7270/Q28917W4
					More data for this Ligand-Target Pair