BDBM105590 US10047086, 108::US10640503, Example 108::US9695168, 108

SMILES: CCn1c2ccc(cc2oc1=O)-c1c(nc(N2CCC(CC2)N(C)C)c2cncn12)-c1ccc(cc1)C#N

InChI Key: InChIKey=OMEQOYPDUQUCQR-UHFFFAOYSA-N

Data: 3 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 105590   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Lysine-specific histone demethylase 1A (Homo sapiens (Human))	BDBM105590 (US10047086, 108 | US10640503, Example 108 | US9695...) Show SMILES CCn1c2ccc(cc2oc1=O)-c1c(nc(N2CCC(CC2)N(C)C)c2cncn12)-c1ccc(cc1)C#N Show InChI InChI=1S/C29H29N7O2/c1-4-35-23-10-9-21(15-25(23)38-29(35)37)27-26(20-7-5-19(16-30)6-8-20)32-28(24-17-31-18-36(24)27)34-13-11-22(12-14-34)33(2)3/h5-10,15,17-18,22H,4,11-14H2,1-3H3	PDB GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	<50	n/a	n/a	n/a	n/a	7.5	25
Incyte Corporation US Patent					Assay Description LANCE LSD1/KDM1A demethylase assay¿10 uL of 1 nM LSD-1 enzyme (ENZO BML-SE544-0050) in the assay buffer (50 mM Tris, pH 7.5, 0.01% Tween-20, 25 mM Na...				US Patent US9695168 (2017) BindingDB Entry DOI: 10.7270/Q2SX6BCD
					More data for this Ligand-Target Pair
Lysine-specific histone demethylase 1A (Homo sapiens (Human))	BDBM105590 (US10047086, 108 | US10640503, Example 108 | US9695...) Show SMILES CCn1c2ccc(cc2oc1=O)-c1c(nc(N2CCC(CC2)N(C)C)c2cncn12)-c1ccc(cc1)C#N Show InChI InChI=1S/C29H29N7O2/c1-4-35-23-10-9-21(15-25(23)38-29(35)37)27-26(20-7-5-19(16-30)6-8-20)32-28(24-17-31-18-36(24)27)34-13-11-22(12-14-34)33(2)3/h5-10,15,17-18,22H,4,11-14H2,1-3H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	<50	n/a	n/a	n/a	n/a	n/a	n/a
Incyte Corporation US Patent					Assay Description LANCE LSD1/KDM1A demethylase assay-10 μL of 1 nM LSD-1 enzyme (ENZO BML-SE544-0050) in the assay buffer (50 mM Tris, pH 7.5, 0.01% Tween-20, 25 ...				US Patent US10640503 (2020)
					More data for this Ligand-Target Pair
Lysine-specific histone demethylase 1A (Homo sapiens (Human))	BDBM105590 (US10047086, 108 | US10640503, Example 108 | US9695...) Show SMILES CCn1c2ccc(cc2oc1=O)-c1c(nc(N2CCC(CC2)N(C)C)c2cncn12)-c1ccc(cc1)C#N Show InChI InChI=1S/C29H29N7O2/c1-4-35-23-10-9-21(15-25(23)38-29(35)37)27-26(20-7-5-19(16-30)6-8-20)32-28(24-17-31-18-36(24)27)34-13-11-22(12-14-34)33(2)3/h5-10,15,17-18,22H,4,11-14H2,1-3H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	<50	n/a	n/a	n/a	n/a	7.5	n/a
Incyte Corporation US Patent					Assay Description LANCE LSD1/KDM1A demethylase assay-10 μL of 1 nM LSD-1 enzyme (ENZO BML-SE544-0050) in the assay buffer (50 mM Tris, pH 7.5, 0.01% Tween-20, 25 ...				US Patent US10047086 (2018) BindingDB Entry DOI: 10.7270/Q28917W4
					More data for this Ligand-Target Pair