BDBM106789 (5Z)‐5‐({2‐[(3‐ chlorophenyl)methoxy]phenyl}methylidene)imidazolidine‐ 2,4‐dione (comp#a)

SMILES: Clc1cccc(COc2ccccc2\C=C2/NC(=O)NC2=O)c1

InChI Key: InChIKey=FHOXIASCFNKVKS-ZROIWOOFSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 106789   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Tyrosine-protein phosphatase non-receptor type 2 (Homo sapiens (Human))	BDBM106789 ((5Z)‐5‐({2‐[(3‐ chlorophen...) Show SMILES Clc1cccc(COc2ccccc2\C=C2/NC(=O)NC2=O)c1 Show InChI InChI=1S/C17H13ClN2O3/c18-13-6-3-4-11(8-13)10-23-15-7-2-1-5-12(15)9-14-16(21)20-17(22)19-14/h1-9H,10H2,(H2,19,20,21,22)/b14-9-	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.68E+4	n/a	n/a	n/a	n/a	6.0	37
Tianjin Medical University					Assay Description The enzyme activity was measured using p-nitrophenyl phosphate (pNPP) as substrate in a 96-well plate and by detecting the absorbance at 405 nm for t...				Chem Biol Drug Des 82: 595-602 (2013) Article DOI: 10.1111/cbdd.12189 BindingDB Entry DOI: 10.7270/Q2K64GQP
					More data for this Ligand-Target Pair
Protein-tyrosine phosphatase 1B (Homo sapiens (Human))	BDBM106789 ((5Z)‐5‐({2‐[(3‐ chlorophen...) Show SMILES Clc1cccc(COc2ccccc2\C=C2/NC(=O)NC2=O)c1 Show InChI InChI=1S/C17H13ClN2O3/c18-13-6-3-4-11(8-13)10-23-15-7-2-1-5-12(15)9-14-16(21)20-17(22)19-14/h1-9H,10H2,(H2,19,20,21,22)/b14-9-	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.74E+4	n/a	n/a	n/a	n/a	6.0	37
Tianjin Medical University					Assay Description The enzyme activity was measured using p-nitrophenyl phosphate (pNPP) as substrate in a 96-well plate and by detecting the absorbance at 405 nm for t...				Chem Biol Drug Des 82: 595-602 (2013) Article DOI: 10.1111/cbdd.12189 BindingDB Entry DOI: 10.7270/Q2K64GQP
					More data for this Ligand-Target Pair