BDBM107145 US8592415, 30

SMILES: CC(=O)SCC(=O)Nc1cccc(c1)-c1cnc2ccccc2n1

InChI Key: InChIKey=JMAFKCNVKFAFKL-UHFFFAOYSA-N

Data: 4 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 107145   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Tyrosine-protein kinase JAK3 (Homo sapiens (Human))	BDBM107145 (US8592415, 30) Show SMILES CC(=O)SCC(=O)Nc1cccc(c1)-c1cnc2ccccc2n1 Show InChI InChI=1S/C18H15N3O2S/c1-12(22)24-11-18(23)20-14-6-4-5-13(9-14)17-10-19-15-7-2-3-8-16(15)21-17/h2-10H,11H2,1H3,(H,20,23)	PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	KEGG PC cid PC sid UniChem Similars	US Patent	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Reaction Biology Corp.; Synerga Limited US Patent					Assay Description In vitro kinase enzyme assay using Jak3, Jak2, Jak1, and Tyk2.				US Patent US8592415 (2013) BindingDB Entry DOI: 10.7270/Q218354P
					More data for this Ligand-Target Pair
Non-receptor tyrosine-protein kinase TYK2 (Homo sapiens (Human))	BDBM107145 (US8592415, 30) Show SMILES CC(=O)SCC(=O)Nc1cccc(c1)-c1cnc2ccccc2n1 Show InChI InChI=1S/C18H15N3O2S/c1-12(22)24-11-18(23)20-14-6-4-5-13(9-14)17-10-19-15-7-2-3-8-16(15)21-17/h2-10H,11H2,1H3,(H,20,23)	PDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	KEGG PC cid PC sid UniChem Similars	US Patent	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Reaction Biology Corp.; Synerga Limited US Patent					Assay Description In vitro kinase enzyme assay using Jak3, Jak2, Jak1, and Tyk2.				US Patent US8592415 (2013) BindingDB Entry DOI: 10.7270/Q218354P
					More data for this Ligand-Target Pair
Tyrosine-protein kinase JAK1 (Homo sapiens (Human))	BDBM107145 (US8592415, 30) Show SMILES CC(=O)SCC(=O)Nc1cccc(c1)-c1cnc2ccccc2n1 Show InChI InChI=1S/C18H15N3O2S/c1-12(22)24-11-18(23)20-14-6-4-5-13(9-14)17-10-19-15-7-2-3-8-16(15)21-17/h2-10H,11H2,1H3,(H,20,23)	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	KEGG PC cid PC sid UniChem Similars	US Patent	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Reaction Biology Corp.; Synerga Limited US Patent					Assay Description In vitro kinase enzyme assay using Jak3, Jak2, Jak1, and Tyk2.				US Patent US8592415 (2013) BindingDB Entry DOI: 10.7270/Q218354P
					More data for this Ligand-Target Pair
Tyrosine-protein kinase JAK2 (Homo sapiens (Human))	BDBM107145 (US8592415, 30) Show SMILES CC(=O)SCC(=O)Nc1cccc(c1)-c1cnc2ccccc2n1 Show InChI InChI=1S/C18H15N3O2S/c1-12(22)24-11-18(23)20-14-6-4-5-13(9-14)17-10-19-15-7-2-3-8-16(15)21-17/h2-10H,11H2,1H3,(H,20,23)	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	KEGG PC cid PC sid UniChem Similars	US Patent	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Reaction Biology Corp.; Synerga Limited US Patent					Assay Description In vitro kinase enzyme assay using Jak3, Jak2, Jak1, and Tyk2.				US Patent US8592415 (2013) BindingDB Entry DOI: 10.7270/Q218354P
					More data for this Ligand-Target Pair