BDBM107215 US8598345, Table 1-1

SMILES: O=C(Nc1ccccc1)c1cc(Oc2cccnc2)ccn1

InChI Key: InChIKey=CAGCUYYFOBKZDY-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 107215   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Metabotropic glutamate receptor 5 (Rattus norvegicus (Rat))	BDBM107215 (US8598345, Table 1-1) Show SMILES O=C(Nc1ccccc1)c1cc(Oc2cccnc2)ccn1 Show InChI InChI=1S/C17H13N3O2/c21-17(20-13-5-2-1-3-6-13)16-11-14(8-10-19-16)22-15-7-4-9-18-12-15/h1-12H,(H,20,21)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	3.46E+3	n/a	n/a	n/a	n/a	n/a	n/a
Vanderbilt University US Patent					Assay Description mGluR5 activity was determined in a cell-based assay.				US Patent US8598345 (2013) BindingDB Entry DOI: 10.7270/Q2RR1WX8
					More data for this Ligand-Target Pair