BDBM107229 US8598345, Table 1-15

SMILES: Clc1cccc(NC(=O)c2cc(Oc3cccnc3)ccn2)n1

InChI Key: InChIKey=LBSBYZVEDGLNRA-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 107229   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Metabotropic glutamate receptor 5 (Rattus norvegicus (Rat))	BDBM107229 (US8598345, Table 1-15) Show SMILES Clc1cccc(NC(=O)c2cc(Oc3cccnc3)ccn2)n1 Show InChI InChI=1S/C16H11ClN4O2/c17-14-4-1-5-15(20-14)21-16(22)13-9-11(6-8-19-13)23-12-3-2-7-18-10-12/h1-10H,(H,20,21,22)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	1.92E+3	n/a	n/a	n/a	n/a	n/a	n/a
Vanderbilt University US Patent					Assay Description mGluR5 activity was determined in a cell-based assay.				US Patent US8598345 (2013) BindingDB Entry DOI: 10.7270/Q2RR1WX8
					More data for this Ligand-Target Pair