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SMILES: CCc1cccc(NC(=O)c2cc(Oc3cccnc3)ccn2)n1

InChI Key: InChIKey=YXOSIRXCCBWPLW-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 107232   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Metabotropic glutamate receptor 5


(Rattus norvegicus (Rat))		BDBM107232
PNG
(US8598345, Table 1-18)
Show SMILES CCc1cccc(NC(=O)c2cc(Oc3cccnc3)ccn2)n1
Show InChI InChI=1S/C18H16N4O2/c1-2-13-5-3-7-17(21-13)22-18(23)16-11-14(8-10-20-16)24-15-6-4-9-19-12-15/h3-12H,2H2,1H3,(H,21,22,23)
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Similars
US Patent
n/an/a 226n/an/an/an/an/an/a



Vanderbilt University

US Patent


Assay Description
mGluR5 activity was determined in a cell-based assay.

US Patent US8598345 (2013)


BindingDB Entry DOI: 10.7270/Q2RR1WX8
More data for this
Ligand-Target Pair