BDBM107236 US8598345, Table 1-22

SMILES: COc1cccc(NC(=O)c2cc(Oc3cccnc3)ccn2)n1

InChI Key: InChIKey=PBWMGRSFRHTTAQ-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 107236   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Metabotropic glutamate receptor 5 (Rattus norvegicus (Rat))	BDBM107236 (US8598345, Table 1-22) Show SMILES COc1cccc(NC(=O)c2cc(Oc3cccnc3)ccn2)n1 Show InChI InChI=1S/C17H14N4O3/c1-23-16-6-2-5-15(20-16)21-17(22)14-10-12(7-9-19-14)24-13-4-3-8-18-11-13/h2-11H,1H3,(H,20,21,22)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	379	n/a	n/a	n/a	n/a	n/a	n/a
Vanderbilt University US Patent					Assay Description mGluR5 activity was determined in a cell-based assay.				US Patent US8598345 (2013) BindingDB Entry DOI: 10.7270/Q2RR1WX8
					More data for this Ligand-Target Pair