BDBM107247 US8598345, Table 1-33

SMILES: CN(c1cccnc1)c1ccnc(c1)C(=O)Nc1nccs1

InChI Key: InChIKey=BWKFDAQAIGCQTN-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 107247   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Metabotropic glutamate receptor 5 (Rattus norvegicus (Rat))	BDBM107247 (US8598345, Table 1-33) Show SMILES CN(c1cccnc1)c1ccnc(c1)C(=O)Nc1nccs1 Show InChI InChI=1S/C15H13N5OS/c1-20(12-3-2-5-16-10-12)11-4-6-17-13(9-11)14(21)19-15-18-7-8-22-15/h2-10H,1H3,(H,18,19,21)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	5.59E+3	n/a	n/a	n/a	n/a	n/a	n/a
Vanderbilt University US Patent					Assay Description mGluR5 activity was determined in a cell-based assay.				US Patent US8598345 (2013) BindingDB Entry DOI: 10.7270/Q2RR1WX8
					More data for this Ligand-Target Pair