BDBM107261 US8598345, 203::US8598345, Table 1-48/2-7

SMILES: O=C(Nc1ccccn1)c1cc(Oc2cncnc2)ccn1

InChI Key: InChIKey=FELLWSPKJLIKKD-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 107261   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Metabotropic glutamate receptor 5 (Homo sapiens (Human))	BDBM107261 (US8598345, 203 | US8598345, Table 1-48/2-7) Show SMILES O=C(Nc1ccccn1)c1cc(Oc2cncnc2)ccn1 Show InChI InChI=1S/C15H11N5O2/c21-15(20-14-3-1-2-5-19-14)13-7-11(4-6-18-13)22-12-8-16-10-17-9-12/h1-10H,(H,19,20,21)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	84	n/a	n/a	n/a	n/a	n/a	n/a
Vanderbilt University US Patent					Assay Description mGluR5 activity was determined in a cell-based assay.				US Patent US8598345 (2013) BindingDB Entry DOI: 10.7270/Q2RR1WX8
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor (Rattus norvegicus (Rat))	BDBM107261 (US8598345, 203 | US8598345, Table 1-48/2-7) Show SMILES O=C(Nc1ccccn1)c1cc(Oc2cncnc2)ccn1 Show InChI InChI=1S/C15H11N5O2/c21-15(20-14-3-1-2-5-19-14)13-7-11(4-6-18-13)22-12-8-16-10-17-9-12/h1-10H,(H,19,20,21)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	114	n/a	n/a	n/a	n/a	n/a	n/a
Vanderbilt University US Patent					Assay Description mGluR5 activity was determined in a cell-based assay.				US Patent US8598345 (2013) BindingDB Entry DOI: 10.7270/Q2RR1WX8
					More data for this Ligand-Target Pair