BDBM107263 US8598345, 205::US8598345, Table 1-49/2-9

SMILES: Fc1ccc(NC(=O)c2cc(Oc3cncnc3)ccn2)nc1

InChI Key: InChIKey=VJCZZCNDIYFAPL-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 107263   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Metabotropic glutamate receptor 5 (Homo sapiens (Human))	BDBM107263 (US8598345, 205 | US8598345, Table 1-49/2-9) Show SMILES Fc1ccc(NC(=O)c2cc(Oc3cncnc3)ccn2)nc1 Show InChI InChI=1S/C15H10FN5O2/c16-10-1-2-14(20-6-10)21-15(22)13-5-11(3-4-19-13)23-12-7-17-9-18-8-12/h1-9H,(H,20,21,22)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	364	n/a	n/a	n/a	n/a	n/a	n/a
Vanderbilt University US Patent					Assay Description mGluR5 activity was determined in a cell-based assay.				US Patent US8598345 (2013) BindingDB Entry DOI: 10.7270/Q2RR1WX8
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 5 (Rattus norvegicus (Rat))	BDBM107263 (US8598345, 205 | US8598345, Table 1-49/2-9) Show SMILES Fc1ccc(NC(=O)c2cc(Oc3cncnc3)ccn2)nc1 Show InChI InChI=1S/C15H10FN5O2/c16-10-1-2-14(20-6-10)21-15(22)13-5-11(3-4-19-13)23-12-7-17-9-18-8-12/h1-9H,(H,20,21,22)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	389	n/a	n/a	n/a	n/a	n/a	n/a
Vanderbilt University US Patent					Assay Description mGluR5 activity was determined in a cell-based assay.				US Patent US8598345 (2013) BindingDB Entry DOI: 10.7270/Q2RR1WX8
					More data for this Ligand-Target Pair