BindingDB logo
myBDB logout

null

SMILES: CN(C(=O)Oc1ccc(F)cc1)[C@@]1(C)CN(C[C@@H]1c1ccc(Cl)cc1)C(=O)C1CCN(CC1)c1ccc(F)cn1

InChI Key: InChIKey=SAZDHHKXZAYNLA-VIZCGCQYSA-N

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 109722   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Neuromedin-K receptor


(Homo sapiens (Human))		BDBM109722
PNG
(US8618303, 12)
Show SMILES CN(C(=O)Oc1ccc(F)cc1)[C@@]1(C)CN(C[C@@H]1c1ccc(Cl)cc1)C(=O)C1CCN(CC1)c1ccc(F)cn1 |r|
Show InChI InChI=1S/C30H31ClF2N4O3/c1-30(35(2)29(39)40-25-10-7-23(32)8-11-25)19-37(18-26(30)20-3-5-22(31)6-4-20)28(38)21-13-15-36(16-14-21)27-12-9-24(33)17-34-27/h3-12,17,21,26H,13-16,18-19H2,1-2H3/t26-,30+/m1/s1
Reactome pathway
KEGG

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars
US Patent
 7.60n/an/an/an/an/an/an/an/a



Hoffmann-La Roche Inc.

US Patent


Assay Description
hNK3 receptor binding experiment were performed using [3H]SR142801 (Catalog No. TRK1035, specific activity: 74.0 Ci/mmol, Amersham, GE Healthcare UK ...

US Patent US8618303 (2013)


BindingDB Entry DOI: 10.7270/Q2TB15KK
More data for this
Ligand-Target Pair