BDBM109905 US8609647, 49

SMILES: CCNC(=O)N1CCCC11CCCN(C1)c1ncnc2[nH]ccc12

InChI Key: InChIKey=OSLXDTSEKCUZTF-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 109905   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Tyrosine-protein kinase JAK3 (Homo sapiens (Human))	BDBM109905 (US8609647, 49) Show SMILES CCNC(=O)N1CCCC11CCCN(C1)c1ncnc2[nH]ccc12 Show InChI InChI=1S/C17H24N6O/c1-2-18-16(24)23-10-4-7-17(23)6-3-9-22(11-17)15-13-5-8-19-14(13)20-12-21-15/h5,8,12H,2-4,6-7,9-11H2,1H3,(H,18,24)(H,19,20,21)	PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	92	n/a	n/a	n/a	n/a	n/a	n/a
Japan Tobacco Inc. US Patent					Assay Description In the kinase reactions, fused proteins (6His tag-fused hJAK3 kinase domain (aa781-end)) which were coexpressed in Sf21 cells and purified by Ni2+/NT...				US Patent US8609647 (2013) BindingDB Entry DOI: 10.7270/Q29C6W24
					More data for this Ligand-Target Pair