BDBM109908 US8609647, 53
SMILES: N#CCCN1CCCC11CCN(C1)c1ncnc2[nH]ccc12
InChI Key: InChIKey=YUVAVYDWVOPQLT-UHFFFAOYSA-N
Data: 1 IC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Tyrosine-protein kinase JAK3 (Homo sapiens (Human)) | BDBM109908 (US8609647, 53) | PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 56 | n/a | n/a | n/a | n/a | n/a | n/a |
Japan Tobacco Inc. US Patent | Assay Description In the kinase reactions, fused proteins (6His tag-fused hJAK3 kinase domain (aa781-end)) which were coexpressed in Sf21 cells and purified by Ni2+/NT... | US Patent US8609647 (2013) BindingDB Entry DOI: 10.7270/Q29C6W24 | |||||||||||
More data for this Ligand-Target Pair |