BDBM111133 US9695179, 128
SMILES: CNC(=S)N1N=C(CC1c1ccccc1)c1c(-c2ccccc2)c2cc(Cl)ccc2[nH]c1=O
InChI Key: InChIKey=SJESTDSBHNANEG-UHFFFAOYSA-N
Data: 1 IC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
BRD4-BD1-BD2 (Homo sapiens (Human)) | BDBM111133![]() (US9695179, 128) | PDB GoogleScholar AffyNet ![]() | Purchase PC cid PC sid UniChem | US Patent | n/a | n/a | 1.63E+4 | n/a | n/a | n/a | n/a | n/a | 25 |
ConverGene LLC US Patent | Assay Description The interactions between test compounds and BRD4 protein containing both bromodomain 1 and bromodomain 2 were measured with human BRD4 protein with N... | US Patent US9695179 (2017) BindingDB Entry DOI: 10.7270/Q21G0JF6 | |||||||||||
More data for this Ligand-Target Pair |