BDBM111138 US9682940, 28

SMILES: NC(=O)c1ccc(cc1)S(=O)(=O)N1CCC(CC1)c1n[nH]c2ccc(cc12)C(c1ccc(Cl)cc1)c1ccc(Cl)cc1

InChI Key: InChIKey=DYKHLLSEPFVFBV-UHFFFAOYSA-N

Data: 2 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 111138   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Cannabinoid receptor 2 (Homo sapiens (Human))	BDBM111138 (US9682940, 28) Show SMILES NC(=O)c1ccc(cc1)S(=O)(=O)N1CCC(CC1)c1n[nH]c2ccc(cc12)C(c1ccc(Cl)cc1)c1ccc(Cl)cc1 Show InChI InChI=1S/C32H28Cl2N4O3S/c33-25-8-1-20(2-9-25)30(21-3-10-26(34)11-4-21)24-7-14-29-28(19-24)31(37-36-29)22-15-17-38(18-16-22)42(40,41)27-12-5-23(6-13-27)32(35)39/h1-14,19,22,30H,15-18H2,(H2,35,39)(H,36,37)	PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a
Janssen Pharmaceutica NV US Patent					Assay Description CB1 and CB2 receptors are Gi-coupled GPCR. Activation of CB1 and CB2 receptors results in a decrease in cAMP production. An inverse agonist of the CB...				US Patent US9682940 (2017) BindingDB Entry DOI: 10.7270/Q2M61HD7
					More data for this Ligand-Target Pair
Cannabinoid receptor 1 (Homo sapiens (Human))	BDBM111138 (US9682940, 28) Show SMILES NC(=O)c1ccc(cc1)S(=O)(=O)N1CCC(CC1)c1n[nH]c2ccc(cc12)C(c1ccc(Cl)cc1)c1ccc(Cl)cc1 Show InChI InChI=1S/C32H28Cl2N4O3S/c33-25-8-1-20(2-9-25)30(21-3-10-26(34)11-4-21)24-7-14-29-28(19-24)31(37-36-29)22-15-17-38(18-16-22)42(40,41)27-12-5-23(6-13-27)32(35)39/h1-14,19,22,30H,15-18H2,(H2,35,39)(H,36,37)	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	134	n/a	n/a	n/a	n/a
Janssen Pharmaceutica NV US Patent					Assay Description CB1 and CB2 receptors are Gi-coupled GPCR. Activation of CB1 and CB2 receptors results in a decrease in cAMP production. An inverse agonist of the CB...				US Patent US9682940 (2017) BindingDB Entry DOI: 10.7270/Q2M61HD7
					More data for this Ligand-Target Pair