null

SMILES: COC(=O)c1ccccc1Cn1nc(N2CCN(CC2)S(=O)(=O)C(F)(F)F)c2cc(ccc12)C(c1ccc(Cl)cc1)c1ccc(Cl)cc1

InChI Key: InChIKey=HKAZHPDEJCQSPU-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 111140   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Cannabinoid receptor 2 (Homo sapiens (Human))	BDBM111140 (US9682940, 30) Show SMILES COC(=O)c1ccccc1Cn1nc(N2CCN(CC2)S(=O)(=O)C(F)(F)F)c2cc(ccc12)C(c1ccc(Cl)cc1)c1ccc(Cl)cc1 Show InChI InChI=1S/C34H29Cl2F3N4O4S/c1-47-33(44)28-5-3-2-4-25(28)21-43-30-15-10-24(31(22-6-11-26(35)12-7-22)23-8-13-27(36)14-9-23)20-29(30)32(40-43)41-16-18-42(19-17-41)48(45,46)34(37,38)39/h2-15,20,31H,16-19,21H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a
Janssen Pharmaceutica NV US Patent					Assay Description CB1 and CB2 receptors are Gi-coupled GPCR. Activation of CB1 and CB2 receptors results in a decrease in cAMP production. An inverse agonist of the CB...				US Patent US9682940 (2017) BindingDB Entry DOI: 10.7270/Q2M61HD7
					More data for this Ligand-Target Pair
Cannabinoid receptor 1 (Homo sapiens (Human))	BDBM111140 (US9682940, 30) Show SMILES COC(=O)c1ccccc1Cn1nc(N2CCN(CC2)S(=O)(=O)C(F)(F)F)c2cc(ccc12)C(c1ccc(Cl)cc1)c1ccc(Cl)cc1 Show InChI InChI=1S/C34H29Cl2F3N4O4S/c1-47-33(44)28-5-3-2-4-25(28)21-43-30-15-10-24(31(22-6-11-26(35)12-7-22)23-8-13-27(36)14-9-23)20-29(30)32(40-43)41-16-18-42(19-17-41)48(45,46)34(37,38)39/h2-15,20,31H,16-19,21H2,1H3	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a
Janssen Pharmaceutica NV US Patent					Assay Description CB1 and CB2 receptors are Gi-coupled GPCR. Activation of CB1 and CB2 receptors results in a decrease in cAMP production. An inverse agonist of the CB...				US Patent US9682940 (2017) BindingDB Entry DOI: 10.7270/Q2M61HD7
					More data for this Ligand-Target Pair