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SMILES: FC(F)(F)S(=O)(=O)N1CCC(CC1)c1nn(-c2nccs2)c2ccc(cc12)C(c1ccc(Cl)cc1)c1ccc(Cl)cc1

InChI Key: InChIKey=MPOUHKAFHTYLIW-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 111146   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Cannabinoid receptor 2 (Homo sapiens (Human))	BDBM111146 (US9682940, 37) Show SMILES FC(F)(F)S(=O)(=O)N1CCC(CC1)c1nn(-c2nccs2)c2ccc(cc12)C(c1ccc(Cl)cc1)c1ccc(Cl)cc1 Show InChI InChI=1S/C29H23Cl2F3N4O2S2/c30-22-6-1-18(2-7-22)26(19-3-8-23(31)9-4-19)21-5-10-25-24(17-21)27(36-38(25)28-35-13-16-41-28)20-11-14-37(15-12-20)42(39,40)29(32,33)34/h1-10,13,16-17,20,26H,11-12,14-15H2	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a
Janssen Pharmaceutica NV US Patent					Assay Description CB1 and CB2 receptors are Gi-coupled GPCR. Activation of CB1 and CB2 receptors results in a decrease in cAMP production. An inverse agonist of the CB...				US Patent US9682940 (2017) BindingDB Entry DOI: 10.7270/Q2M61HD7
					More data for this Ligand-Target Pair
Cannabinoid receptor 1 (Homo sapiens (Human))	BDBM111146 (US9682940, 37) Show SMILES FC(F)(F)S(=O)(=O)N1CCC(CC1)c1nn(-c2nccs2)c2ccc(cc12)C(c1ccc(Cl)cc1)c1ccc(Cl)cc1 Show InChI InChI=1S/C29H23Cl2F3N4O2S2/c30-22-6-1-18(2-7-22)26(19-3-8-23(31)9-4-19)21-5-10-25-24(17-21)27(36-38(25)28-35-13-16-41-28)20-11-14-37(15-12-20)42(39,40)29(32,33)34/h1-10,13,16-17,20,26H,11-12,14-15H2	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	8	n/a	n/a	n/a	n/a
Janssen Pharmaceutica NV US Patent					Assay Description CB1 and CB2 receptors are Gi-coupled GPCR. Activation of CB1 and CB2 receptors results in a decrease in cAMP production. An inverse agonist of the CB...				US Patent US9682940 (2017) BindingDB Entry DOI: 10.7270/Q2M61HD7
					More data for this Ligand-Target Pair