BDBM113058 US8633208, 1
SMILES: c1cn(cn1)-c1ccc2nc(ncc2c1)-c1ccccc1
InChI Key: InChIKey=CSZGXYBGYFNSCO-UHFFFAOYSA-N
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
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Alpha-2A adrenergic receptor (Homo sapiens) | BDBM113058![]() (US8633208, 1) | MMDB B.MOAD DrugBank GoogleScholar AffyNet ![]() | Purchase PC cid PC sid UniChem Similars | Article PubMed | 2.24E+6 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Barcelona Curated by ChEMBL | Assay Description Displacement of [3H]RX821002 from alpha2-AR in human brain frontal cortex incubated for 30 mins by liquid scintillation spectrometry | J Med Chem 63: 3610-3633 (2020) Article DOI: 10.1021/acs.jmedchem.9b02080 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Amine oxidase (flavin-containing) A (Homo sapiens (Human)) | BDBM113058![]() (US8633208, 1) | PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet ![]() | Purchase PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 220 | n/a | n/a | n/a | n/a | n/a | n/a |
Rottapharm S.p.A US Patent | Assay Description Inhibitory activity of compounds was evaluated by a homogeneous luminescent method, the MAO-Glo Assay (Promega), measuring the monoamine oxidase acti... | US Patent US8633208 (2014) BindingDB Entry DOI: 10.7270/Q23J3BMD | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Amine oxidase [flavin-containing] B (Homo sapiens (Human)) | BDBM113058![]() (US8633208, 1) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet ![]() | Purchase PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Rottapharm S.p.A US Patent | Assay Description Inhibitory activity of compounds was evaluated by a homogeneous luminescent method, the MAO-Glo Assay (Promega), measuring the monoamine oxidase acti... | US Patent US8633208 (2014) BindingDB Entry DOI: 10.7270/Q23J3BMD | |||||||||||
More data for this Ligand-Target Pair |