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BDBM118172 US8653125, Ia-14

SMILES: Fc1ccccc1-c1cccc(NC(=O)[C@@H]2CC[C@@H](CC2)NC(=O)c2ccccc2)c1

InChI Key: InChIKey=LTWJKLJPPJDNGM-TYKWCNGQSA-N

Data: 1 IC50

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   Substructure
Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 118172   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Neuropeptide Y receptor type 5


(Mus musculus (Mouse))		BDBM118172
PNG
(US8653125, Ia-14)
Show SMILES Fc1ccccc1-c1cccc(NC(=O)[C@@H]2CC[C@@H](CC2)NC(=O)c2ccccc2)c1 |r,wU:18.22,15.15,(8.67,-3.08,;8.67,-1.54,;10,-.77,;10,.77,;8.67,1.54,;7.34,.77,;7.34,-.77,;6,-1.54,;6,-3.08,;4.67,-3.85,;3.33,-3.08,;3.33,-1.54,;2,-.77,;.67,-1.54,;.67,-3.08,;-.67,-.77,;-.67,.77,;-2,1.54,;-3.33,.77,;-3.33,-.77,;-2,-1.54,;-4.67,1.54,;-6,.77,;-6,-.77,;-7.34,1.54,;-8.67,.77,;-10,1.54,;-10,3.08,;-8.67,3.85,;-7.34,3.08,;4.67,-.77,)|
Show InChI InChI=1S/C26H25FN2O2/c27-24-12-5-4-11-23(24)20-9-6-10-22(17-20)29-26(31)19-13-15-21(16-14-19)28-25(30)18-7-2-1-3-8-18/h1-12,17,19,21H,13-16H2,(H,28,30)(H,29,31)/t19-,21+
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PC cid
PC sid
UniChem
US Patent
n/an/a 4.10n/an/an/an/a7.425



Shionogi Co., Ltd.

US Patent


Assay Description
cDNA sequence encoding mouse NPY Y5 receptor (Biochem. Biophys. Acta 1328: 83-89, 1997) was cloned in the expression vector (pME18S, Takebe et al. Mo...

US Patent US8653125 (2014)


BindingDB Entry DOI: 10.7270/Q2VQ31BN
More data for this
Ligand-Target Pair