BDBM119655 US8680275, 24

SMILES: CCOc1ccc2ccccc2c1C(=O)N1CCC2CN(C2C1)c1nc(C)cc(C)n1

InChI Key: InChIKey=FMDLLJUHVSZUIY-UHFFFAOYSA-N

Data: 2 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 119655   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Orexin receptor type 2 (Homo sapiens (Human))	BDBM119655 (US8680275, 24) Show SMILES CCOc1ccc2ccccc2c1C(=O)N1CCC2CN(C2C1)c1nc(C)cc(C)n1 Show InChI InChI=1S/C25H28N4O2/c1-4-31-22-10-9-18-7-5-6-8-20(18)23(22)24(30)28-12-11-19-14-29(21(19)15-28)25-26-16(2)13-17(3)27-25/h5-10,13,19,21H,4,11-12,14-15H2,1-3H3	PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	6	-10.4	n/a	n/a	n/a	n/a	n/a	n/a	4
Janssen Pharmaceutica NV US Patent					Assay Description HEK293 stably expressing human orexin-2 receptor (Genebank accession number NM 001526) were grown to confluency in DMEM/F12 (Gibco, Cat #11039), in D...				US Patent US8680275 (2014) BindingDB Entry DOI: 10.7270/Q2WH2NPF
					More data for this Ligand-Target Pair
Orexin receptor type 1 (Homo sapiens (Human))	BDBM119655 (US8680275, 24) Show SMILES CCOc1ccc2ccccc2c1C(=O)N1CCC2CN(C2C1)c1nc(C)cc(C)n1 Show InChI InChI=1S/C25H28N4O2/c1-4-31-22-10-9-18-7-5-6-8-20(18)23(22)24(30)28-12-11-19-14-29(21(19)15-28)25-26-16(2)13-17(3)27-25/h5-10,13,19,21H,4,11-12,14-15H2,1-3H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	44	-9.32	n/a	n/a	n/a	n/a	n/a	n/a	4
Janssen Pharmaceutica NV US Patent					Assay Description Chinese ovary cells (CHO) stably expressing human orexin 1 receptor (Genebank accession number NM 001526) were grown to confluency in DMEM/F12 (Gibco...				US Patent US8680275 (2014) BindingDB Entry DOI: 10.7270/Q2WH2NPF
					More data for this Ligand-Target Pair