BDBM119859 US8691993, 8

SMILES: OC(=O)Cc1cc(C2CCN(CC2)S(=O)(=O)c2ccc(Cl)cc2)c2cc(F)ccc2c1

InChI Key: InChIKey=KTCVCRWYGGSUDM-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 119859   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Prostaglandin D2 receptor 2 (Homo sapiens (Human))	BDBM119859 (US8691993, 8) Show SMILES OC(=O)Cc1cc(C2CCN(CC2)S(=O)(=O)c2ccc(Cl)cc2)c2cc(F)ccc2c1 Show InChI InChI=1S/C23H21ClFNO4S/c24-18-2-5-20(6-3-18)31(29,30)26-9-7-16(8-10-26)21-12-15(13-23(27)28)11-17-1-4-19(25)14-22(17)21/h1-6,11-12,14,16H,7-10,13H2,(H,27,28)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	42	n/a	n/a	n/a	n/a	n/a	37
Hoffmann-La Roche Inc. US Patent					Assay Description Calcium Flux Assay Using Fluorometric Imaging Plate Reader (FLIPR). Buffer containing dye (from the FLIPR® Calcium 3 Assay Kit from Molecular D...				US Patent US8691993 (2014) BindingDB Entry DOI: 10.7270/Q2348J11
					More data for this Ligand-Target Pair