BDBM120755 US8703761, 1-8

SMILES: COc1ccccc1C(=O)NC(C)(C)C(=O)Nc1nc(c(Cc2ccccc2)s1)-c1ccccc1

InChI Key: InChIKey=WHGVLJWIORAZAW-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 120755   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
acyl coA-diacylglycerol acyl transferase 1 (DGAT1) (Homo sapiens (Human))	BDBM120755 (US8703761, 1-8) Show SMILES COc1ccccc1C(=O)NC(C)(C)C(=O)Nc1nc(c(Cc2ccccc2)s1)-c1ccccc1 Show InChI InChI=1S/C28H27N3O3S/c1-28(2,31-25(32)21-16-10-11-17-22(21)34-3)26(33)30-27-29-24(20-14-8-5-9-15-20)23(35-27)18-19-12-6-4-7-13-19/h4-17H,18H2,1-3H3,(H,31,32)(H,29,30,33)	UniProtKB/TrEMBL GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	8.5	n/a	n/a	n/a	n/a	7.5	4
Novartis AG US Patent					Assay Description The enzyme preparation used in this assay is a membrane preparation from Sf9 cells overexpressing human (His)6DGAT1. During all steps samples were ch...				US Patent US8703761 (2014) BindingDB Entry DOI: 10.7270/Q2057DM1
					More data for this Ligand-Target Pair