BDBM120757 US8703761, 1-29

SMILES: CC(C)(NC(=O)c1ccccn1)C(=O)Nc1nc(c(Cc2ccccc2)s1)-c1ccccc1

InChI Key: InChIKey=MMSKSKHNOBUUEA-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 120757   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
acyl coA-diacylglycerol acyl transferase 1 (DGAT1) (Homo sapiens (Human))	BDBM120757 (US8703761, 1-29) Show SMILES CC(C)(NC(=O)c1ccccn1)C(=O)Nc1nc(c(Cc2ccccc2)s1)-c1ccccc1 Show InChI InChI=1S/C26H24N4O2S/c1-26(2,30-23(31)20-15-9-10-16-27-20)24(32)29-25-28-22(19-13-7-4-8-14-19)21(33-25)17-18-11-5-3-6-12-18/h3-16H,17H2,1-2H3,(H,30,31)(H,28,29,32)	UniProtKB/TrEMBL GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	3.5	n/a	n/a	n/a	n/a	7.5	4
Novartis AG US Patent					Assay Description The enzyme preparation used in this assay is a membrane preparation from Sf9 cells overexpressing human (His)6DGAT1. During all steps samples were ch...				US Patent US8703761 (2014) BindingDB Entry DOI: 10.7270/Q2057DM1
					More data for this Ligand-Target Pair