BDBM120767 US8703761, 6-1

SMILES: CC(C)(NC(=O)c1ccc(OC(F)(F)F)cc1)C(=O)Nc1nc(c(Oc2ccc(F)cc2)s1)-c1ccc(F)cc1

InChI Key: InChIKey=MJTZVNZDKYNJTC-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 120767   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
acyl coA-diacylglycerol acyl transferase 1 (DGAT1) (Homo sapiens (Human))	BDBM120767 (US8703761, 6-1) Show SMILES CC(C)(NC(=O)c1ccc(OC(F)(F)F)cc1)C(=O)Nc1nc(c(Oc2ccc(F)cc2)s1)-c1ccc(F)cc1 Show InChI InChI=1S/C27H20F5N3O4S/c1-26(2,35-22(36)16-5-11-20(12-6-16)39-27(30,31)32)24(37)34-25-33-21(15-3-7-17(28)8-4-15)23(40-25)38-19-13-9-18(29)10-14-19/h3-14H,1-2H3,(H,35,36)(H,33,34,37)	UniProtKB/TrEMBL GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	910	n/a	n/a	n/a	n/a	7.5	4
Novartis AG US Patent					Assay Description The enzyme preparation used in this assay is a membrane preparation from Sf9 cells overexpressing human (His)6DGAT1. During all steps samples were ch...				US Patent US8703761 (2014) BindingDB Entry DOI: 10.7270/Q2057DM1
					More data for this Ligand-Target Pair