BDBM123337 US8742106, 1.32
SMILES: Cc1ccc(CNC(=O)COc2cc(c3c(nn(C)c3n2)-c2ccccc2)C(F)(F)F)cc1
InChI Key: InChIKey=NISUEUIBEZZNRO-UHFFFAOYSA-N
Data: 2 Kd
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Orexin receptor type 2 (Homo sapiens (Human)) | BDBM123337![]() (US8742106, 1.32) | PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | n/a | 1.38E+3 | n/a | n/a | n/a | 7.5 | 4 |
Novartis AG US Patent | Assay Description For crude cell membrane preparations, cells (CHO, Chinese hamster ovary or HEK, human embryonic kidney) expressing human orexin 1 or human orexin 2 r... | US Patent US8742106 (2014) BindingDB Entry DOI: 10.7270/Q22V2DSW | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Orexin receptor type 1 (Homo sapiens (Human)) | BDBM123337![]() (US8742106, 1.32) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | n/a | 2.60E+3 | n/a | n/a | n/a | 7.5 | 4 |
Novartis AG US Patent | Assay Description For crude cell membrane preparations, cells (CHO, Chinese hamster ovary or HEK, human embryonic kidney) expressing human orexin 1 or human orexin 2 r... | US Patent US8742106 (2014) BindingDB Entry DOI: 10.7270/Q22V2DSW | |||||||||||
More data for this Ligand-Target Pair |