BDBM123552 US8748624, 38

SMILES: OC(=O)CCNC(=O)c1ccc(cn1)-c1cc(ccc1CNc1ccc(c(Cl)c1)-c1cccc(c1Cl)C(F)(F)F)C(F)(F)F

InChI Key: InChIKey=ZRWLHJNYUSQDDV-UHFFFAOYSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 123552   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Glucagon receptor (Homo sapiens (Human))	BDBM123552 (US8748624, 38) Show SMILES OC(=O)CCNC(=O)c1ccc(cn1)-c1cc(ccc1CNc1ccc(c(Cl)c1)-c1cccc(c1Cl)C(F)(F)F)C(F)(F)F Show InChI InChI=1S/C30H21Cl2F6N3O3/c31-24-13-19(7-8-20(24)21-2-1-3-23(27(21)32)30(36,37)38)40-14-16-4-6-18(29(33,34)35)12-22(16)17-5-9-25(41-15-17)28(44)39-11-10-26(42)43/h1-9,12-13,15,40H,10-11,14H2,(H,39,44)(H,42,43)	PDB MMDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	22.5	n/a	n/a	n/a	n/a	n/a	n/a	7.4	n/a
Janssen Pharmaceutica NV US Patent					Assay Description The binding assay was performed by a filtration method in a 384 well format. Membranes at a final protein concentration of 6 μg/well were incuba...				US Patent US8748624 (2014) BindingDB Entry DOI: 10.7270/Q29885QP
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