BDBM123585 US8748624, 78

SMILES: OC(=O)CCNC(=O)c1ccc(cn1)-c1cc(c(Cl)cc1CNc1ccc(c(Cl)c1)-c1ccc(Cl)cc1)C(F)(F)F

InChI Key: InChIKey=UAZPERHGCRSLES-UHFFFAOYSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 123585   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Glucagon receptor (Homo sapiens (Human))	BDBM123585 (US8748624, 78) Show SMILES OC(=O)CCNC(=O)c1ccc(cn1)-c1cc(c(Cl)cc1CNc1ccc(c(Cl)c1)-c1ccc(Cl)cc1)C(F)(F)F Show InChI InChI=1S/C29H21Cl3F3N3O3/c30-19-4-1-16(2-5-19)21-7-6-20(12-24(21)31)37-15-18-11-25(32)23(29(33,34)35)13-22(18)17-3-8-26(38-14-17)28(41)36-10-9-27(39)40/h1-8,11-14,37H,9-10,15H2,(H,36,41)(H,39,40)	PDB MMDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	24	n/a	n/a	n/a	n/a	n/a	n/a	7.4	n/a
Janssen Pharmaceutica NV US Patent					Assay Description The binding assay was performed by a filtration method in a 384 well format. Membranes at a final protein concentration of 6 μg/well were incuba...				US Patent US8748624 (2014) BindingDB Entry DOI: 10.7270/Q29885QP
					More data for this Ligand-Target Pair