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SMILES: Cc1cc(NCc2cc(Cl)c(cc2-c2ccc(nc2)C(=O)NCCC(O)=O)C(F)(F)F)ccc1-c1ccc(Cl)cc1

InChI Key: InChIKey=BNXXOXNANURZKE-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 123586   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Glucagon receptor


(Homo sapiens (Human))		BDBM123586
PNG
(US8748624, 79)
Show SMILES Cc1cc(NCc2cc(Cl)c(cc2-c2ccc(nc2)C(=O)NCCC(O)=O)C(F)(F)F)ccc1-c1ccc(Cl)cc1
Show InChI InChI=1S/C30H24Cl2F3N3O3/c1-17-12-22(7-8-23(17)18-2-5-21(31)6-3-18)37-16-20-13-26(32)25(30(33,34)35)14-24(20)19-4-9-27(38-15-19)29(41)36-11-10-28(39)40/h2-9,12-15,37H,10-11,16H2,1H3,(H,36,41)(H,39,40)
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Similars
US Patent
 24n/an/an/an/an/an/a7.4n/a



Janssen Pharmaceutica NV

US Patent


Assay Description
The binding assay was performed by a filtration method in a 384 well format. Membranes at a final protein concentration of 6 μg/well were incuba...

US Patent US8748624 (2014)


BindingDB Entry DOI: 10.7270/Q29885QP
More data for this
Ligand-Target Pair