BDBM123898 US8754113, I-3-4

SMILES: Cn1cc(cn1)-c1ccc2sc(Cc3nnc(CC(=O)NC4(CC4)C#N)o3)nc2c1

InChI Key: InChIKey=XGIFOCZIFOTCPD-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 123898   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Endothelial lipase (Homo sapiens (Human))	BDBM123898 (US8754113, I-3-4) Show SMILES Cn1cc(cn1)-c1ccc2sc(Cc3nnc(CC(=O)NC4(CC4)C#N)o3)nc2c1 Show InChI InChI=1S/C20H17N7O2S/c1-27-10-13(9-22-27)12-2-3-15-14(6-12)23-19(30-15)8-18-26-25-17(29-18)7-16(28)24-20(11-21)4-5-20/h2-3,6,9-10H,4-5,7-8H2,1H3,(H,24,28)	KEGG UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	4	n/a	n/a	n/a	n/a	n/a	37
Shionogi & Co., Ltd. US Patent					Assay Description After the present compound dissolved in DMSO was added to become 0.5% DMSO to the reaction buffer consisting of 20 mM tris hydrochloric acid (pH7.4),...				US Patent US8754113 (2014) BindingDB Entry DOI: 10.7270/Q27D2SVD
					More data for this Ligand-Target Pair