BDBM123907 US8754113, I-3-48
SMILES: O=C(Cc1nnc(Cc2nc3ccc(cc3s2)C2=CCOCC2)o1)NC1(CC1)C#N
InChI Key: InChIKey=NWBCIHPRDVLWLS-UHFFFAOYSA-N
Data: 1 IC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Endothelial lipase (Homo sapiens (Human)) | BDBM123907 (US8754113, I-3-48) | KEGG UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 8 | n/a | n/a | n/a | n/a | n/a | 37 |
Shionogi & Co., Ltd. US Patent | Assay Description After the present compound dissolved in DMSO was added to become 0.5% DMSO to the reaction buffer consisting of 20 mM tris hydrochloric acid (pH7.4),... | US Patent US8754113 (2014) BindingDB Entry DOI: 10.7270/Q27D2SVD | |||||||||||
More data for this Ligand-Target Pair |