BDBM124240 N,N'-(biphenyl-4,4'-diyl)bis(1-benzoylpiperidine-4-carboxamide) (14)
SMILES: O=C(Nc1ccc(cc1)-c1ccc(NC(=O)C2CCN(CC2)C(=O)c2ccccc2)cc1)C1CCN(CC1)C(=O)c1ccccc1
InChI Key: InChIKey=QRBHPRNSIBXUOF-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 124240 Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kcal/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
Tyrosine-protein phosphatase non-receptor type 2
(Homo sapiens (Human)) | BDBM124240
(N,N'-(biphenyl-4,4'-diyl)bis(1-benzoylpipe...)Show SMILES O=C(Nc1ccc(cc1)-c1ccc(NC(=O)C2CCN(CC2)C(=O)c2ccccc2)cc1)C1CCN(CC1)C(=O)c1ccccc1 Show InChI InChI=1S/C38H38N4O4/c43-35(29-19-23-41(24-20-29)37(45)31-7-3-1-4-8-31)39-33-15-11-27(12-16-33)28-13-17-34(18-14-28)40-36(44)30-21-25-42(26-22-30)38(46)32-9-5-2-6-10-32/h1-18,29-30H,19-26H2,(H,39,43)(H,40,44) | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet 
| PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 7.62E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Jiangnan University
| Assay Description
IC50 values were determined by pNPP assay. |
Bioorg Med Chem Lett 24: 1889-94 (2014)
Article DOI: 10.1016/j.bmcl.2014.03.015
BindingDB Entry DOI: 10.7270/Q2PC3122 |
More data for this
Ligand-Target Pair | |
Tyrosine-protein phosphatase non-receptor type 1
(Homo sapiens (Human)) | BDBM124240
(N,N'-(biphenyl-4,4'-diyl)bis(1-benzoylpipe...)Show SMILES O=C(Nc1ccc(cc1)-c1ccc(NC(=O)C2CCN(CC2)C(=O)c2ccccc2)cc1)C1CCN(CC1)C(=O)c1ccccc1 Show InChI InChI=1S/C38H38N4O4/c43-35(29-19-23-41(24-20-29)37(45)31-7-3-1-4-8-31)39-33-15-11-27(12-16-33)28-13-17-34(18-14-28)40-36(44)30-21-25-42(26-22-30)38(46)32-9-5-2-6-10-32/h1-18,29-30H,19-26H2,(H,39,43)(H,40,44) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 2.65E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Jiangnan University
| Assay Description
IC50 values were determined by pNPP assay. |
Bioorg Med Chem Lett 24: 1889-94 (2014)
Article DOI: 10.1016/j.bmcl.2014.03.015
BindingDB Entry DOI: 10.7270/Q2PC3122 |
More data for this
Ligand-Target Pair | |
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