BDBM125995 US8772288, 34

SMILES: Cc1ccc(cc1-c1ccc2c(NC(=O)C22CCC(O)CC2)c1)C(=O)NC1CC1

InChI Key: InChIKey=LZMWFPIUZDOPGD-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 125995   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Mitogen-activated protein kinase 14 (Homo sapiens (Human))	BDBM125995 (US8772288, 34) Show SMILES Cc1ccc(cc1-c1ccc2c(NC(=O)C22CCC(O)CC2)c1)C(=O)NC1CC1 |(-4.1,1.33,;-2.77,2.1,;-2.77,3.64,;-1.44,4.41,;-.1,3.64,;-.1,2.1,;-1.44,1.33,;-1.44,-.21,;-.1,-.98,;-.1,-2.52,;-1.44,-3.29,;-2.77,-2.52,;-3.91,-3.55,;-3.29,-4.95,;-4.06,-6.29,;-1.76,-4.79,;-2.16,-6.28,;-1.07,-7.37,;.42,-6.97,;1.51,-8.06,;.82,-5.48,;-.27,-4.39,;-2.77,-.98,;1.23,4.41,;2.56,3.64,;1.23,5.95,;2.56,6.72,;4.1,6.72,;3.33,8.06,)| Show InChI InChI=1S/C24H26N2O3/c1-14-2-3-16(22(28)25-17-5-6-17)12-19(14)15-4-7-20-21(13-15)26-23(29)24(20)10-8-18(27)9-11-24/h2-4,7,12-13,17-18,27H,5-6,8-11H2,1H3,(H,25,28)(H,26,29)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	1.40	n/a	n/a	n/a	n/a	7.5	25
Almirall, S.A. US Patent					Assay Description Enzymatic activity assay was performed in 96-well microtiter plates (Corning, catalog number #3686) using a total volume of 50 ul of an assay buffer ...				US Patent US8772288 (2014) BindingDB Entry DOI: 10.7270/Q2T152BM
					More data for this Ligand-Target Pair