BDBM125997 US8772288, 40
SMILES: Cc1ccc(cc1-c1ccc2c(NC(=O)C22CCC(CC2)N2CCOCC2)c1)C(=O)NC1CC1
InChI Key: InChIKey=NFGQINUSUMNGDA-UHFFFAOYSA-N
Data: 1 IC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Mitogen-activated protein kinase 14 (Homo sapiens (Human)) | BDBM125997 (US8772288, 40) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 1 | n/a | n/a | n/a | n/a | 7.5 | 25 |
Almirall, S.A. US Patent | Assay Description Enzymatic activity assay was performed in 96-well microtiter plates (Corning, catalog number #3686) using a total volume of 50 ul of an assay buffer ... | US Patent US8772288 (2014) BindingDB Entry DOI: 10.7270/Q2T152BM | |||||||||||
More data for this Ligand-Target Pair |