BDBM12626 (2S,5R)-1-[(2S)-2-amino-4-methylpentanoyl]-5-ethynylpyrrolidine-2-carbonitrile::(2S,5R)-5-ethynyl-1-L-leucylpyrrolidine-2-carbonitrile::C5-substituted pyrrolidine 14

SMILES: CC(C)C[C@H](N)C(=O)N1[C@H](CC[C@H]1C#N)C#C

InChI Key: InChIKey=XXTBOOXAFXMJIZ-SRVKXCTJSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 12626   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Dipeptidyl peptidase 4 (Homo sapiens (Human))	BDBM12626 ((2S,5R)-1-[(2S)-2-amino-4-methylpentanoyl]-5-ethyn...) Show SMILES CC(C)C[C@H](N)C(=O)N1[C@H](CC[C@H]1C#N)C#C |r| Show InChI InChI=1S/C13H19N3O/c1-4-10-5-6-11(8-14)16(10)13(17)12(15)7-9(2)3/h1,9-12H,5-7,15H2,2-3H3/t10-,11-,12-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	8	-10.9	n/a	n/a	n/a	n/a	n/a	7.5	22
Abbott Laboratories					Assay Description The DPP4 activity resulted in the formation of the fluorescent product amidomethylcoumarin (AMC), which was monitored by excitation at 355 nm and mea...				J Med Chem 49: 6416-20 (2006) Article DOI: 10.1021/jm060777o BindingDB Entry DOI: 10.7270/Q2M043M1
					More data for this Ligand-Target Pair