BDBM12641 (2S,5R)-1-(N-cyclopentylglycyl)-5-prop-1-ynylpyrrolidine-2-carbonitrile::(2S,5R)-1-[2-(cyclopentylamino)acetyl]-5-(prop-1-yn-1-yl)pyrrolidine-2-carbonitrile::C5-substituted pyrrolidine 34

SMILES: CC#C[C@H]1CC[C@@H](C#N)N1C(=O)CNC1CCCC1

InChI Key: InChIKey=HXRNWGQZAVPNHT-KBPBESRZSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 12641   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Dipeptidyl peptidase 4 (Homo sapiens (Human))	BDBM12641 ((2S,5R)-1-(N-cyclopentylglycyl)-5-prop-1-ynylpyrro...) Show SMILES CC#C[C@H]1CC[C@@H](C#N)N1C(=O)CNC1CCCC1 |r| Show InChI InChI=1S/C15H21N3O/c1-2-5-13-8-9-14(10-16)18(13)15(19)11-17-12-6-3-4-7-12/h12-14,17H,3-4,6-9,11H2,1H3/t13-,14-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	959	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories					Assay Description The DPP4 activity resulted in the formation of the fluorescent product amidomethylcoumarin (AMC), which was monitored by excitation at 355 nm and mea...				J Med Chem 49: 6416-20 (2006) Article DOI: 10.1021/jm060777o BindingDB Entry DOI: 10.7270/Q2M043M1
					More data for this Ligand-Target Pair